Factors Beyond Traditional Predictors Influencing Outcomes Following Acute Coronary Syndrome
Sári Csaba
KÁROLY RÁCZ CONSERVATIVE MEDICINE PROGRAM
Dr. Fekete Andrea
GOKVI Tanácsterem
2026-02-17 14:00:00
Hormonal Regulations
Dr. Igaz Péter
Dr. Andréka Péter
Dr. Torzsa Péter
Dr. Szabados Eszter
Dr. Mócsai Attila
Dr. Szilveszter Bálint
Dr. Szili-Török Tamás
This research investigates the effects of CR and sex-related differences on the prognosis of patients in Hungary following ACS. Women typically experience inferior outcomes, as evidenced by elevated mortality rates, delays in care, and less aggressive treatment protocols. Several factors contribute to the poorer outcomes observed in female patients, including older age at presentation, a higher prevalence of comorbid conditions, atypical symptomatology, diagnostic challenges (NSTEMI and MINOCA), and lower rates of engagement in secondary prevention. The primary objectives of this study were to evaluate the impact of a CCR program on survival among early post-MI survivors and to analyze sex-related differences in clinical presentation, management practices, and long-term outcomes. The findings suggest that CR is an effective intervention that enhances survival rates; however, despite established guidelines, participation rates remain alarmingly low, indicating an urgent need for policy reforms.
Sex disparities in outcomes are multifactorial. Some adverse early outcomes may be attributable to biases within the healthcare system, biological factors, or the challenges posed by comorbidities. Our analysis also revealed age-related differences, indicating that younger patients benefit significantly from timely revascularization, irrespective of sex. Conversely, in the older population, particularly among women, timely revascularization and adherence to prescribed therapy are essential yet often inadequately addressed. In conclusion, the findings highlight the prognostic significance of CR post-MI, underscore the persistent sex disparities in management and outcomes, and emphasize the necessity for systemic interventions. These interventions should enhance adherence to clinical guidelines, enforce relevant policies, and improve access to rehabilitation services. Special attention should be directed toward vulnerable groups, including elderly women, diabetic patients, and those with NSTEMI, to mitigate mortality rates and improve long-term prognoses. In summary, enhancing participation in CR through policy adaptations, the development of outpatient programs, and the utilization of electronic health tools, while addressing gender-specific management gaps, can substantially improve long-term survival and quality of life for patients following myocardial infarction.
